Scrypt forces hashing to touch a sizeable scratchpad of memory, which made it expensive to implement in early ASICs and briefly preserved GPU mining. Dedicated Scrypt ASICs arrived anyway in 2014; today machines like the Antminer L9 (16 GH/s) define the network.
Scrypt's economic peculiarity is merged mining: Dogecoin accepts Litecoin's proof-of-work via AuxPoW, so every modern Scrypt miner earns LTC and DOGE simultaneously — often with DOGE contributing half or more of total revenue.
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